| Number | Service (From/To) | General Details | Operator | | 4 | Ayr to Glasgow | Only this direction, Sat (every 30 mins) Sun (every 60 mins) | Western Scottish |
| Via Ayr-Newton on Ayr-Heathfield-Prestwick Airport (Rail Station) ..... more |
| | Ayr to Kilmarnock | Only this direction, Sat (6 trips) Sun (1 trip) | " |
| Via Ayr-Newton on Ayr-Heathfield-Prestwick Airport (Rail Station) ..... more |
| | Fenwick to Ayr | Only this direction, Sat (1 trip) | " |
| Via Kilmarnock-Beansburn-Kilmarnock (Bus Station)-Riccarton ..... more |
| | Glasgow to Ayr | Only this direction, Sat (every 30 mins) Sun (every 60 mins) | " |
| Via Glasgow-Tradeston-Govanhill-Shawlands-Newlands-Merrylee ..... more |
| | Kilmarnock to Ayr | Only this direction, Sat (5 trips) Sun (4 trips) | " |
| Via Kilmarnock-Riccarton-Caprington-Bogend-Symington-Hansel Village ..... more |
| 14 | Ayr to Irvine | Sat (every 45 mins) Sun (every 60 mins) | " |
| Via Newton on Ayr-Heathfield-Prestwick-Prestwick Airport (Rail Station) ..... more |
| | Ayr to Troon | Only this direction, Sun (1 trip) | " |
| Via Newton on Ayr-Heathfield-Prestwick-Prestwick Airport (Rail Station) ..... more |
| | Ayr to Irvine | Evenings only, Sat (1 trip) | " |
| Via Ayr-Newton on Ayr-Heathfield-Prestwick-Prestwick Airport (Rail Station) ..... more |
| | Troon to Ayr | Only this direction, Sun (1 trip) | " |
| Via Barassie-Troon-Monkton-Prestwick-Prestwick Airport (Rail Station) ..... more |
| 218 | Glasgow to Girvan | Mon to Sat (1 trip) | Scotrail |
| Via Kilmarnock-Troon-Prestwick Airport-Prestwick-Ayr-Maybole |
| | Glasgow to Stranraer | Mon to Sat (1 trip) | " |
| Via Kilmarnock-Troon-Prestwick Airport-Prestwick-Ayr-Maybole ..... more |
| | Kilmarnock to Girvan | Mon to Sat (3 trips) | " |
| Via Troon-Prestwick Airport-Prestwick-Ayr-Maybole |
| | Kilmarnock to Stranraer | Mon to Sat (5 trips) | " |
| Via Troon-Prestwick Airport-Prestwick-Ayr-Maybole-Girvan ..... more |
| 221 | Glasgow to Ayr | Mon to Sat (every 60 mins) | " |
| Via Paisley (Gilmour Street Rail Station)-Johnstone-Kilwinning ..... more |
| | Glasgow to Ayr | Mon to Sun (every 60 mins) | " |
| Via Paisley (Gilmour Street Rail Station)-Johnstone-Kilwinning ..... more |
| 263 | Dundee to Ayr | Summer Only, not every week, Thu (1 trip) | Fishers Tours |
| Via Newport On Tay-St Michaels-Leuchars-Guardbridge-Dairsie ..... more |
| 585 | Ardrossan to Ayr | Only this direction, Sat (7 trips) Sun (1 trip) | Western Scottish |
| Via Saltcoats-Rail Station-Stevenston-Auchenharvie-Irvine ..... more |
| | Ayr to Ardrossan | Only this direction, Sat (4 trips) Sun (2 trips) | " |
| Via Ayr-Newton on Ayr-Heathfield-Prestwick Airport (Rail Station) ..... more |
| | Ayr to Largs | Only this direction, Sat (every 30 mins) Sun (3 trips) | " |
| Via Ayr-Newton on Ayr-Heathfield-Prestwick Airport (Rail Station) ..... more |
| | Largs to Ayr | Only this direction, Sat (every 30 mins) Sun (4 trips) | " |
| Via Fairlie-West Kilbride-Seamill-Ardrossan-Saltcoats-Rail Station ..... more |
| X77 | Alloway to Glasgow | Only this direction, Sat (2 trips) | " |
| Via Seafield-Ayr-Bus Station-Newton on Ayr-Heathfield-Prestwick ..... more |
| | Ayr to Glasgow | Only this direction, Sat (1 trip) | " |
| Via Seafield-Doonfoot-Alloway-Ayr (St Leonards Road)-Ayr ..... more |
| | Ayr to Glasgow | Sat (every 30 mins) Sun (every 60 mins) | " |
| Via Newton on Ayr-Heathfield-Prestwick-Prestwick Airport (Rail Station) ..... more |
| | Ayr to Glasgow | Sat (6 trips) Sun (2 trips) | " |
| Via Newton on Ayr-Heathfield-Prestwick-Prestwick Airport (Rail Station) ..... more |
| | Glasgow to Alloway | Only this direction, Sat (2 trips) | " |
| Via Glasgow-Fenwick-Hansel Village-Prestwick Airport (Rail Station) ..... more |
| X99 | Glasgow to Prestwick Airport | Mon to Sun (1 trip) | Dodds |